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Clinical manufacturing of CAR T cells: foundation of a promising therapy

The treatment of cancer patients with autologous T cells expressing a chimeric antigen receptor (CAR) is one of the most promising adoptive cellular therapy approaches. Reproducible manufacturing of high-quality, clinical-grade CAR-T cell products is a prerequisite for the wide application of this t...

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Dades bibliogràfiques
Publicat a:Mol Ther Oncolytics
Autors principals: Wang, Xiuyan, Rivière, Isabelle
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909095/
https://ncbi.nlm.nih.gov/pubmed/27347557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.15
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