Global Manufacturing of CAR T Cell Therapy

Immunotherapy using chimeric antigen receptor-modified T cells has demonstrated high response rates in patients with B cell malignancies, and chimeric antigen receptor T cell therapy is now being investigated in several hematologic and solid tumor types. Chimeric antigen receptor T cells are generat...

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Detalhes bibliográficos
Main Authors: Bruce L. Levine, James Miskin, Keith Wonnacott, Christopher Keir
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017-03-01
Colecção:Molecular Therapy: Methods & Clinical Development
Assuntos:
chimeric antigen receptor
T lymphocytes
manufacturing
lentiviral vector
global regulatory environment
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2329050116302029
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