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Apolipoprotein E4 Prevents Growth of Malaria at the Intraerythrocyte Stage: Implications For Differences in Racial Susceptibility to Alzheimer’s Disease

Apolipoprotein E 4 (ApoE 4) has been linked to pathogenesis of Alzheimer’s disease and has been suggested to be maintained through evolutionary pressure via a protective role in malaria infection. We evaluated Plasmodium falciparum viability at the intraerythrocyte stage by exposure to plasma from h...

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Detalhes bibliográficos
Publicado no:J Health Care Poor Underserved
Main Authors: Fujioka, Hisashi, Phelix, Clyde F., Friedland, Robert P., Zhu, Xiongwei, Perry, Elizabeth A., Castellani, Rudy J., Perry, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909051/
https://ncbi.nlm.nih.gov/pubmed/24241262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1353/hpu.2014.0009
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