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IGF-1 protects tubular epithelial cells during injury via activation of ERK/MAPK signaling pathway
Injury of renal tubular epithelial cells can induce acute renal failure and obstructive nephropathy. Previous studies have shown that administration of insulin-like growth factor-1 (IGF-1) ameliorates the renal injury in a mouse unilateral ureteral obstruction (UUO) model, whereas the underlying mec...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4908659/ https://ncbi.nlm.nih.gov/pubmed/27301852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28066 |
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