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IGF-1 protects tubular epithelial cells during injury via activation of ERK/MAPK signaling pathway

Injury of renal tubular epithelial cells can induce acute renal failure and obstructive nephropathy. Previous studies have shown that administration of insulin-like growth factor-1 (IGF-1) ameliorates the renal injury in a mouse unilateral ureteral obstruction (UUO) model, whereas the underlying mec...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Zengbin, Yu, Yang, Niu, Lei, Fei, Aihua, Pan, Shuming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908659/
https://ncbi.nlm.nih.gov/pubmed/27301852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28066
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