Dexmedetomidine protects against oxygen-glucose deprivation/reoxygenation injury-induced apoptosis via the p38 MAPK/ERK signalling pathway

OBJECTIVE: To investigate the protective effects of dexmedetomidine (DEX) in oxygen-glucose deprivation/reoxygenation (OGD/R) injury, which is involved in a number of ischaemic diseases. METHODS: An in vitro OGD/R injury model was generated using mouse Neuro 2A neuroblastoma (N2A) cells. Different c...

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Vydáno v:J Int Med Res
Hlavní autoři: Wang, Ke, Zhu, Yuekun
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2017
Témata:
Research Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971521/
https://ncbi.nlm.nih.gov/pubmed/29210287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060517734460
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