INPP4B is an oncogenic regulator in human colon cancer

Inositol polyphosphate 4-phosphatase type II (INPP4B) negatively regulates phosphatidylinositol 3-kinase signaling and is a tumor suppressor in some types of cancers. However, we have found that it is frequently upregulated in human colon cancer cells. Here we show that silencing of INPP4B blocks ac...

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Pubblicato in:Oncogene
Autori principali: Guo, S T, Chi, M N, Yang, R H, Guo, X Y, Zan, L K, Wang, C Y, Xi, Y F, Jin, L, Croft, A, Tseng, H-Y, Yan, X G, Farrelly, M, Wang, F H, Lai, F, Wang, J F, Li, Y P, Ackland, S, Scott, R, Agoulnik, I U, Hondermarck, H, Thorne, R F, Liu, T, Zhang, X D, Jiang, C C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908438/
https://ncbi.nlm.nih.gov/pubmed/26411369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.361
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