CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis

Adipose tissue lipolysis produces glycerol and nonesterified fatty acids (NEFA) that serve as energy sources during nutrient scarcity. Adipose tissue lipolysis is tightly regulated and excessive lipolysis causes hepatic steatosis, as NEFA released from adipose tissue constitutes a major source of TG...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Park, Jong-Gil, Xu, Xu, Cho, Sungyun, Hur, Kyu Yeon, Lee, Myung-Shik, Kersten, Sander, Lee, Ann-Hwee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908383/
https://ncbi.nlm.nih.gov/pubmed/27301791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27938
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