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Linear effects models of signaling pathways from combinatorial perturbation data

Motivation: Perturbations constitute the central means to study signaling pathways. Interrupting components of the pathway and analyzing observed effects of those interruptions can give insight into unknown connections within the signaling pathway itself, as well as the link from the pathway to the...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Szczurek, Ewa, Beerenwinkel, Niko
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908352/
https://ncbi.nlm.nih.gov/pubmed/27307630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw268
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