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Linear effects models of signaling pathways from combinatorial perturbation data

Motivation: Perturbations constitute the central means to study signaling pathways. Interrupting components of the pathway and analyzing observed effects of those interruptions can give insight into unknown connections within the signaling pathway itself, as well as the link from the pathway to the...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Szczurek, Ewa, Beerenwinkel, Niko
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908352/
https://ncbi.nlm.nih.gov/pubmed/27307630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw268
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