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RNAiFold2T: Constraint Programming design of thermo-IRES switches

Motivation: RNA thermometers (RNATs) are cis-regulatory elements that change secondary structure upon temperature shift. Often involved in the regulation of heat shock, cold shock and virulence genes, RNATs constitute an interesting potential resource in synthetic biology, where engineered RNATs cou...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Autores principales: Garcia-Martin, Juan Antonio, Dotu, Ivan, Fernandez-Chamorro, Javier, Lozano, Gloria, Ramajo, Jorge, Martinez-Salas, Encarnacion, Clote, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908349/
https://ncbi.nlm.nih.gov/pubmed/27307638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw265
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