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Designing synthetic RNAs to determine the relevance of structural motifs in picornavirus IRES elements

The function of Internal Ribosome Entry Site (IRES) elements is intimately linked to their RNA structure. Viral IRES elements are organized in modular domains consisting of one or more stem-loops that harbor conserved RNA motifs critical for internal initiation of translation. A conserved motif is t...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Fernandez-Chamorro, Javier, Lozano, Gloria, Garcia-Martin, Juan Antonio, Ramajo, Jorge, Dotu, Ivan, Clote, Peter, Martinez-Salas, Encarnacion
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823658/
https://ncbi.nlm.nih.gov/pubmed/27053355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24243
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