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Designing synthetic RNAs to determine the relevance of structural motifs in picornavirus IRES elements

The function of Internal Ribosome Entry Site (IRES) elements is intimately linked to their RNA structure. Viral IRES elements are organized in modular domains consisting of one or more stem-loops that harbor conserved RNA motifs critical for internal initiation of translation. A conserved motif is t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Fernandez-Chamorro, Javier, Lozano, Gloria, Garcia-Martin, Juan Antonio, Ramajo, Jorge, Dotu, Ivan, Clote, Peter, Martinez-Salas, Encarnacion
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823658/
https://ncbi.nlm.nih.gov/pubmed/27053355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24243
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