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Magnesium‐dependent folding of a picornavirus IRES element modulates RNA conformation and eIF4G interaction

Internal ribosome entry site (IRES) elements are high‐order RNA structures that promote internal initiation of translation to allow protein synthesis under situations that compromise the general cap‐dependent translation mechanism. Picornavirus IRES elements are highly efficient elements with a modu...

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Autors principals: Lozano, Gloria, Fernandez, Noemi, Martinez‐Salas, Encarnacion
Format: Artigo
Idioma:Inglês
Publicat: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163634/
https://ncbi.nlm.nih.gov/pubmed/24961997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12890
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