RNAiFold2T: Constraint Programming design of thermo-IRES switches

Motivation: RNA thermometers (RNATs) are cis-regulatory elements that change secondary structure upon temperature shift. Often involved in the regulation of heat shock, cold shock and virulence genes, RNATs constitute an interesting potential resource in synthetic biology, where engineered RNATs cou...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Garcia-Martin, Juan Antonio, Dotu, Ivan, Fernandez-Chamorro, Javier, Lozano, Gloria, Ramajo, Jorge, Martinez-Salas, Encarnacion, Clote, Peter
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Ismb 2016 Proceedings July 8 to July 12, 2016, Orlando, Florida
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908349/
https://ncbi.nlm.nih.gov/pubmed/27307638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw265
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