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RNAiFold2T: Constraint Programming design of thermo-IRES switches

Motivation: RNA thermometers (RNATs) are cis-regulatory elements that change secondary structure upon temperature shift. Often involved in the regulation of heat shock, cold shock and virulence genes, RNATs constitute an interesting potential resource in synthetic biology, where engineered RNATs cou...

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Publicat a:Bioinformatics
Autors principals: Garcia-Martin, Juan Antonio, Dotu, Ivan, Fernandez-Chamorro, Javier, Lozano, Gloria, Ramajo, Jorge, Martinez-Salas, Encarnacion, Clote, Peter
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908349/
https://ncbi.nlm.nih.gov/pubmed/27307638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw265
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