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Granulocyte colony‐stimulating factor impairs CD8(+) T cell functionality by interfering with central activation elements

Besides mobilizing stem cells into the periphery, granulocyte colony‐stimulating factor (G‐CSF) has been shown to influence various types of innate and adaptive immune cells. For example, it impairs the effector function of cytotoxic T lymphocytes (CTLs). It is assumed that this effect is mediated i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Exp Immunol
Hauptverfasser: Bunse, C. E., Tischer, S., Lahrberg, J., Oelke, M., Figueiredo, C., Blasczyk, R., Eiz‐Vesper, B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908295/
https://ncbi.nlm.nih.gov/pubmed/26990855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12794
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