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Granulocyte colony‐stimulating factor impairs CD8(+) T cell functionality by interfering with central activation elements

Besides mobilizing stem cells into the periphery, granulocyte colony‐stimulating factor (G‐CSF) has been shown to influence various types of innate and adaptive immune cells. For example, it impairs the effector function of cytotoxic T lymphocytes (CTLs). It is assumed that this effect is mediated i...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Bunse, C. E., Tischer, S., Lahrberg, J., Oelke, M., Figueiredo, C., Blasczyk, R., Eiz‐Vesper, B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908295/
https://ncbi.nlm.nih.gov/pubmed/26990855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12794
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