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Inward rectifier potassium (Kir2.1) channels as end‐stage boosters of endothelium‐dependent vasodilators

KEY POINTS: Increase in endothelial cell (EC) calcium activates calcium‐sensitive intermediate and small conductance potassium (IK and SK) channels, thereby causing hyperpolarization and endothelium‐dependent vasodilatation. Endothelial cells express inward rectifier potassium (Kir) channels, but th...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: Sonkusare, Swapnil K., Dalsgaard, Thomas, Bonev, Adrian D., Nelson, Mark T.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908010/
https://ncbi.nlm.nih.gov/pubmed/26840527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271652
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