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Inward rectifier potassium (Kir2.1) channels as end‐stage boosters of endothelium‐dependent vasodilators

KEY POINTS: Increase in endothelial cell (EC) calcium activates calcium‐sensitive intermediate and small conductance potassium (IK and SK) channels, thereby causing hyperpolarization and endothelium‐dependent vasodilatation. Endothelial cells express inward rectifier potassium (Kir) channels, but th...

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Dades bibliogràfiques
Publicat a:J Physiol
Autors principals: Sonkusare, Swapnil K., Dalsgaard, Thomas, Bonev, Adrian D., Nelson, Mark T.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908010/
https://ncbi.nlm.nih.gov/pubmed/26840527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271652
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