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Inward rectifier potassium (Kir2.1) channels as end‐stage boosters of endothelium‐dependent vasodilators

KEY POINTS: Increase in endothelial cell (EC) calcium activates calcium‐sensitive intermediate and small conductance potassium (IK and SK) channels, thereby causing hyperpolarization and endothelium‐dependent vasodilatation. Endothelial cells express inward rectifier potassium (Kir) channels, but th...

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Bibliografske podrobnosti
izdano v:J Physiol
Main Authors: Sonkusare, Swapnil K., Dalsgaard, Thomas, Bonev, Adrian D., Nelson, Mark T.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908010/
https://ncbi.nlm.nih.gov/pubmed/26840527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271652
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