Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution

OBJECTIVE: Genome-wide association studies (GWAS) for plasma lipid levels have mapped numerous genomic loci, with each region often containing many protein-coding genes. Targeted re-sequencing of exons is a strategy to pinpoint causal variants and genes. METHODS: We performed solution-based hybrid s...

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Publicado no:Atherosclerosis
Main Authors: Patel, Aniruddh P., Peloso, Gina M., Pirruccello, James P., Johansen, Christopher T., Dubé, Joseph B., Larach, Daniel B., Ban, Matthew R., Dallinge-Thie, Geesje M., Gupta, Namrata, Boehnke, Michael, Abecasis, Gonçalo R., Kastelein, John J.P., Kees Hovingh, G., Hegele, Robert A., Rader, Daniel J., Kathiresan, Sekar
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907838/
https://ncbi.nlm.nih.gov/pubmed/27182959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2016.04.011
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