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Exome sequencing and complex disease: practical aspects of rare variant association studies

Genetic association and linkage studies can provide insights into complex disease biology, guiding the development of new diagnostic and therapeutic strategies. Over the past decade, genetic association studies have largely focused on common, easy to measure genetic variants shared between many indi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Do, Ron, Kathiresan, Sekar, Abecasis, Gonçalo R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459641/
https://ncbi.nlm.nih.gov/pubmed/22983955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds387
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