A Puzzle Assembly Strategy for Fabrication of Large Engineered Cartilage Tissue Constructs

Engineering of large articular cartilage tissue constructs remains a challenge as tissue growth is limited by nutrient diffusion. Here, a novel strategy is investigated, generating large constructs through the assembly of individually cultured, interlocking, smaller puzzle-shaped subunits. These con...

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Veröffentlicht in:J Biomech
Hauptverfasser: Nover, Adam B., Jones, Brian K., Yu, William T., Donovan, Daniel S., Podolnick, Jeremy D., Cook, James L., Ateshian, Gerard A., Hung, Clark T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907770/
https://ncbi.nlm.nih.gov/pubmed/26895780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2016.01.023
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