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Role of cytochrome P450 2D6 genetic polymorphism in carvedilol hydroxylation in vitro
Cytochrome P450 2D6 (CYP2D6) is a highly polymorphic enzyme that catalyzes the metabolism of a great number of therapeutic drugs. Up to now, >100 allelic variants of CYP2D6 have been reported. Recently, we identified 22 novel variants in the Chinese population in these variants. The purpose of th...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4907640/ https://ncbi.nlm.nih.gov/pubmed/27354764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S106175 |
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