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Investigating polymorphisms by bioinformatics is a potential cost-effective method to screen for germline mutations in Chinese familial adenomatous polyposis patients

The aim of this study was to investigate germline mutations of the APC, MUTYH and AXIN2 genes in Chinese patients with familial adenomatous polyposis (FAP), and further assess the value of bioinformatics in screening the pathogenic changes predisposing to FAP. APC genes from 11 unrelated FAP patient...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: YANG, JUN, LIU, WEI QING, LI, WEN LIANG, CHEN, CHENG, ZHU, ZHU, HONG, MIN, WANG, ZHI QIANG, DONG, JIAN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907044/
https://ncbi.nlm.nih.gov/pubmed/27347161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4646
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