Humanization of an anti-p185HER2 antibody for human cancer therapy.

The murine monoclonal antibody mumAb4D5, directed against human epidermal growth factor receptor 2 (p185HER2), specifically inhibits proliferation of human tumor cells overexpressing p185HER2. However, the efficacy of mumAb4D5 in human cancer therapy is likely to be limited by a human anti-mouse ant...

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Detalhes bibliográficos
Main Authors: Carter, P, Presta, L, Gorman, C M, Ridgway, J B, Henner, D, Wong, W L, Rowland, A M, Kotts, C, Carver, M E, Shepard, H M
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49066/
https://ncbi.nlm.nih.gov/pubmed/1350088
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