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Release of Entropic Spring Reveals Conformational Coupling Mechanism in the ABC Transporter BtuCD-F
Substrate translocation by ATP-binding cassette (ABC) transporters involves coupling of ATP binding and hydrolysis in the nucleotide-binding domains (NBDs) to conformational changes in the transmembrane domains. We used molecular dynamics simulations to investigate the atomic-level mechanism of conf...
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| 出版年: | Biophys J |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906252/ https://ncbi.nlm.nih.gov/pubmed/27276259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.027 |
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