KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation

Centromere chromatin containing histone H3 variant CENP-A is required for accurate chromosome segregation as a foundation for kinetochore assembly. Human centromere chromatin assembles on a part of the long α-satellite (alphoid) DNA array, where it is flanked by pericentric heterochromatin. Heteroch...

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Udgivet i:Dev Cell
Main Authors: Ohzeki, Jun-ichirou, Shono, Nobuaki, Otake, Koichiro, Martins, Nuno M.C., Kugou, Kazuto, Kimura, Hiroshi, Nagase, Takahiro, Larionov, Vladimir, Earnshaw, William C., Masumoto, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906249/
https://ncbi.nlm.nih.gov/pubmed/27270040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.05.006
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