A minimal CENP-A core is required for nucleation and maintenance of a functional human centromere

Chromatin clusters containing CENP-A, a histone H3 variant, are found in centromeres of multicellular eukaryotes. This study examines the ability of alpha-satellite (alphoid) DNA arrays in different lengths to nucleate CENP-A chromatin and form functional kinetochores de novo. Kinetochore assembly w...

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Detaylı Bibliyografya
Asıl Yazarlar: Okamoto, Yasuhide, Nakano, Megumi, Ohzeki, Jun-ichirou, Larionov, Vladimir, Masumoto, Hiroshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817632/
https://ncbi.nlm.nih.gov/pubmed/17318187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601584
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