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A minimal CENP-A core is required for nucleation and maintenance of a functional human centromere
Chromatin clusters containing CENP-A, a histone H3 variant, are found in centromeres of multicellular eukaryotes. This study examines the ability of alpha-satellite (alphoid) DNA arrays in different lengths to nucleate CENP-A chromatin and form functional kinetochores de novo. Kinetochore assembly w...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1817632/ https://ncbi.nlm.nih.gov/pubmed/17318187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601584 |
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