CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly

CENP-B binds to CENP-B boxes on centromeric satellite DNAs (known as alphoid DNA in humans). CENP-B maintains kinetochore function through interactions with CENP-A nucleosomes and CENP-C. CENP-B binding to transfected alphoid DNA can induce de novo CENP-A assembly, functional centromere and kinetoch...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Otake, Koichiro, Ohzeki, Jun-ichirou, Shono, Nobuaki, Kugou, Kazuto, Okazaki, Koei, Nagase, Takahiro, Yamakawa, Hisashi, Kouprina, Natalay, Larionov, Vladimir, Kimura, Hiroshi, Earnshaw, William C., Masumoto, Hiroshi
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438015/
https://ncbi.nlm.nih.gov/pubmed/32661090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.243303
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