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CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly
CENP-B binds to CENP-B boxes on centromeric satellite DNAs (known as alphoid DNA in humans). CENP-B maintains kinetochore function through interactions with CENP-A nucleosomes and CENP-C. CENP-B binding to transfected alphoid DNA can induce de novo CENP-A assembly, functional centromere and kinetoch...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7438015/ https://ncbi.nlm.nih.gov/pubmed/32661090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.243303 |
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