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The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway

Forms of Parkinson's disease (PD) are associated with lysosomal and autophagic dysfunction. ATP13A2, which is mutated in some types of early-onset Parkinsonism, has been suggested as a regulator of the autophagy–lysosome pathway. However, little is known about the ATP13A2 effectors and how they...

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Foilsithe in:Nat Commun
Main Authors: Bento, Carla F., Ashkenazi, Avraham, Jimenez-Sanchez, Maria, Rubinsztein, David C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906231/
https://ncbi.nlm.nih.gov/pubmed/27278822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11803
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