Simulation of Early Calcific Aortic Valve Disease in a 3D platform: A Role for Myofibroblast Differentiation

PURPOSE: Calcific aortic valve disease (CAVD) is the most prevalent valve disease in the Western world. Recent difficulty in translating experimental results on statins to beneficial clinical effects warrants the need for understanding the role of valvular interstitial cells (VICs) in CAVD. In two-d...

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Bibliographic Details
Published in:J Mol Cell Cardiol
Main Authors: Hjortnaes, Jesper, Goettsch, Claudia, Hutcheson, Joshua D., Camci-Unal, Gulden, Lax, Lilian, Scherer, Katrin, Body, Simon, Schoen, Frederick J., Kluin, Jolanda, Khademhosseini, Ali, Aikawa, Elena
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906202/
https://ncbi.nlm.nih.gov/pubmed/26996755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.03.004
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