Simulation of Early Calcific Aortic Valve Disease in a 3D platform: A Role for Myofibroblast Differentiation

PURPOSE: Calcific aortic valve disease (CAVD) is the most prevalent valve disease in the Western world. Recent difficulty in translating experimental results on statins to beneficial clinical effects warrants the need for understanding the role of valvular interstitial cells (VICs) in CAVD. In two-d...

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Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Hjortnaes, Jesper, Goettsch, Claudia, Hutcheson, Joshua D., Camci-Unal, Gulden, Lax, Lilian, Scherer, Katrin, Body, Simon, Schoen, Frederick J., Kluin, Jolanda, Khademhosseini, Ali, Aikawa, Elena
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906202/
https://ncbi.nlm.nih.gov/pubmed/26996755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.03.004
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