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Simulation of Early Calcific Aortic Valve Disease in a 3D platform: A Role for Myofibroblast Differentiation

PURPOSE: Calcific aortic valve disease (CAVD) is the most prevalent valve disease in the Western world. Recent difficulty in translating experimental results on statins to beneficial clinical effects warrants the need for understanding the role of valvular interstitial cells (VICs) in CAVD. In two-d...

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Publicat a:J Mol Cell Cardiol
Autors principals: Hjortnaes, Jesper, Goettsch, Claudia, Hutcheson, Joshua D., Camci-Unal, Gulden, Lax, Lilian, Scherer, Katrin, Body, Simon, Schoen, Frederick J., Kluin, Jolanda, Khademhosseini, Ali, Aikawa, Elena
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906202/
https://ncbi.nlm.nih.gov/pubmed/26996755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.03.004
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