Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial

Simvastatin reduces the blood concentration of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A reductase, the rate-limiting enzyme in cholesterol synthesis, and thereby reduces the risk of cardiovascular disease. In addition, simvastatin treatment leads to a reduction in fluxes in mitocho...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Rasmussen, Sanne Tofte, Andersen, Jon Trærup, Nielsen, Torben Kjær, Cejvanovic, Vanja, Petersen, Kasper Meidahl, Henriksen, Trine, Weimann, Allan, Lykkesfeldt, Jens, Poulsen, Henrik Enghusen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906137/
https://ncbi.nlm.nih.gov/pubmed/27281490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.05.007
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