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Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial
Simvastatin reduces the blood concentration of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A reductase, the rate-limiting enzyme in cholesterol synthesis, and thereby reduces the risk of cardiovascular disease. In addition, simvastatin treatment leads to a reduction in fluxes in mitocho...
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| 出版年: | Redox Biol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906137/ https://ncbi.nlm.nih.gov/pubmed/27281490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.05.007 |
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