Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials

AIMS: In vitro studies have demonstrated that formation of reactive oxygen species (ROS) contributes to the effect of bactericidal antibiotics. The formation of ROS is not restricted to bacteria, but also occurs in mammalian cells. Oxidative stress is linked to several diseases. This study investiga...

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Udgivet i:Br J Clin Pharmacol
Main Authors: Larsen, Emil List, Cejvanovic, Vanja, Kjær, Laura Kofoed, Pedersen, Morten Thorup, Popik, Sara Daugaard, Hansen, Lina Kallehave, Andersen, Jon Trærup, Jimenez‐Solem, Espen, Broedbaek, Kasper, Petersen, Morten, Weimann, Allan, Henriksen, Trine, Lykkesfeldt, Jens, Torp‐Pedersen, Christian, Poulsen, Henrik Enghusen
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Pharmacodynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510073/
https://ncbi.nlm.nih.gov/pubmed/28185274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13261
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