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MicroRNA 146a locally mediates distal axonal growth of dorsal root ganglia neurons under high glucose and sildenafil conditions

Axonal loss contributes to induction of diabetic peripheral neuropathy. Sildenafil, a phosphodiesterase type 5 inhibitor, ameliorates neurological dysfunction in diabetic peripheral neuropathy. However, the direct effect of high glucose and sildenafil on axonal growth has not been extensively invest...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuroscience
Hauptverfasser: Jia, Longfei, Wang, Lei, Chopp, Michael, Zhang, Yi, Szalad, Alexandra, Zhang, Zheng Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905785/
https://ncbi.nlm.nih.gov/pubmed/27167084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.05.005
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