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MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse

Hyperglycemia impairs nerve fibers of dorsal root ganglia (DRG) neurons, leading to diabetic peripheral neuropathy (DPN). However, the molecular mechanisms underlying DPN are not fully understood. Using a mouse model of type II diabetes (db/db mouse), we found that microRNA-34a (miR-34a) was over-ex...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Jia, Longfei, Chopp, Michael, Wang, Lei, Lu, Xuerong, Zhang, Yi, Szalad, Alexandra, Zhang, Zheng Gang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179937/
https://ncbi.nlm.nih.gov/pubmed/29637443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1047-3
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