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Coinhibitory pathways in the B7-CD28 ligand-receptor family

Immune responses need to be controlled for optimal protective immunity and tolerance. Coinhibitory pathways in the B7-CD28 family provide critical inhibitory signals that regulate immune homeostasis and defense, and protect tissue integrity. These coinhibitory signals limit the strength and duration...

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Detalles Bibliográficos
Publicado en:Immunity
Main Authors: Schildberg, Frank A., Klein, Sarah R., Freeman, Gordon J., Sharpe, Arlene H.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905708/
https://ncbi.nlm.nih.gov/pubmed/27192563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.05.002
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