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B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4
To examine whether B7 costimulation can be mediated by a molecule on T cells that is neither CD28 nor CTLA4, we generated mice lacking both of these receptors. CD28/CTLA4(–/–) mice resemble CD28(–/–) mice in having decreased expression of T-cell activation markers in vivo and decreased T-cell prolif...
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| Main Authors: | , , , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC199576/ https://ncbi.nlm.nih.gov/pubmed/11285307 |
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