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Molecular Pathways: New Signaling Considerations When Targeting Cytoskeletal Balance to Reduce Tumor Growth

The dynamic balance between microtubule extension and actin contraction regulates mammalian cell shape, division and motility, which has made the cytoskeleton an attractive and very successful target for cancer drugs. Numerous compounds in clinical use to reduce tumor growth cause microtubule breakd...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Chakrabarti, Kristi R., Hessler, Lindsay, Bhandary, Lekhana, Martin, Stuart S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905577/
https://ncbi.nlm.nih.gov/pubmed/26463706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0328
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