Pharmacologic regulation of AMPK in breast cancer affects cytoskeletal properties involved with microtentacle formation and re-attachment

The presence of tumor cells in the circulation is associated with a higher risk of metastasis in patients with breast cancer. Circulating breast tumor cells use tubulin-based structures known as microtentacles (McTNs) to re-attach to endothelial cells and arrest in distant organs. McTN formation is...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Chakrabarti, Kristi R., Whipple, Rebecca A., Boggs, Amanda E., Hessler, Lindsay K., Bhandary, Lekhana, Vitolo, Michele I., Thompson, Keyata, Martin, Stuart S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
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Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742178/
https://ncbi.nlm.nih.gov/pubmed/26431377
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