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ROCK inhibition promotes microtentacles that enhance reattachment of breast cancer cells

The presence of circulating tumor cells (CTCs) in blood predicts poor patient outcome and CTC frequency is correlated with higher risk of metastasis. Recently discovered, novel microtubule-based structures, microtentacles, can enhance reattachment of CTCs to the vasculature. Microtentacles are highl...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bhandary, Lekhana, Whipple, Rebecca A., Vitolo, Michele I., Charpentier, Monica S., Boggs, Amanda E., Chakrabarti, Kristi R., Thompson, Keyata N., Martin, Stuart S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467435/
https://ncbi.nlm.nih.gov/pubmed/25749040
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