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ROCK inhibition promotes microtentacles that enhance reattachment of breast cancer cells

The presence of circulating tumor cells (CTCs) in blood predicts poor patient outcome and CTC frequency is correlated with higher risk of metastasis. Recently discovered, novel microtubule-based structures, microtentacles, can enhance reattachment of CTCs to the vasculature. Microtentacles are highl...

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Publicat a:Oncotarget
Autors principals: Bhandary, Lekhana, Whipple, Rebecca A., Vitolo, Michele I., Charpentier, Monica S., Boggs, Amanda E., Chakrabarti, Kristi R., Thompson, Keyata N., Martin, Stuart S.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467435/
https://ncbi.nlm.nih.gov/pubmed/25749040
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