Metastatic breast tumors express increased tau, which promotes microtentacle formation and the reattachment of detached breast tumor cells

The cytoskeletal organization of detached and circulating tumor cells is currently not well-defined and may provide potential targets for new therapies to limit metastatic tumor spread. In vivo, circulating tumor cells reattach in distant tissues via a mechanism that is tubulin-dependent and suppres...

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Autori principali: Matrone, Michael A., Whipple, Rebecca A., Thompson, Keyata, Cho, Edward H., Vitolo, Michele I., Balzer, Eric M., Yoon, Jennifer R., Ioffe, Olga B., Tuttle, Kimberly C., Tan, Ming, Martin, Stuart S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132415/
https://ncbi.nlm.nih.gov/pubmed/20228842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.68
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