Smad4-dependent suppressor pituitary homeobox 2 promotes PPP2R2A-mediated inhibition of Akt pathway in pancreatic cancer

The importance of Pituitary homeobox 2 (Pitx2) in malignancy remains enigmatic, and Pitx2 has not been previously implicated in pancreatic ductal adenocarcinoma (PDAC). In this study, we performed gene expression profiling of human PDAC tissues and identified Pitx2 as a promising candidate. Pitx2 ex...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Qi, Li, Juanjuan, Wu, Wei, Shen, Ruizhe, Jiang, He, Qian, Yuting, Tang, Yanping, Bai, Tingting, Wu, Sheng, Wei, Lumin, Zang, Yi, Zhang, Ji, Wang, Lifu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905467/
https://ncbi.nlm.nih.gov/pubmed/26848620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7158
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