Tp53 Mutation Inhibits Ubiquitination and Degradation of WISP1 via Down-Regulation of Siah1 in Pancreatic Carcinogenesis

Wnt1 inducible signaling pathway protein-1 (WISP1) may play an important role in promoting carcinogenesis. However, the biological function and underlying mechanism of WISP1 in pancreatic carcinogenesis still remains enigmatic. In this study, immunochemistry staining showed that protein levels of WI...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wu, Wei, Liu, Xu, Wei, Lumin, Li, Tong, Zang, Yi, Qian, Yuting, Bai, Tingting, Li, Juanjuan, Xie, Mingping, Zhu, Ying, Wang, Qi, Wang, Lifu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085464/
https://ncbi.nlm.nih.gov/pubmed/30123132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00857
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