Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpression

The global methylation profile and the mutational status of 633 specific epigenetic regulators were analyzed in the pediatric tumor clear cell sarcoma of the kidney (CCSK). Methylation array analyses of 30 CCSKs revealed CCSK tumor DNA to be globally hypermethylated compared to Wilms tumor, normal f...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Karlsson, Jenny, Valind, Anders, Jansson, Caroline, O'Sullivan, Maureen J., Mengelbier, Linda Holmquist, Gisselsson, David
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905462/
https://ncbi.nlm.nih.gov/pubmed/26848979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7152
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