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Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpression

The global methylation profile and the mutational status of 633 specific epigenetic regulators were analyzed in the pediatric tumor clear cell sarcoma of the kidney (CCSK). Methylation array analyses of 30 CCSKs revealed CCSK tumor DNA to be globally hypermethylated compared to Wilms tumor, normal f...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Karlsson, Jenny, Valind, Anders, Jansson, Caroline, O'Sullivan, Maureen J., Mengelbier, Linda Holmquist, Gisselsson, David
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905462/
https://ncbi.nlm.nih.gov/pubmed/26848979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7152
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