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More challenges ahead—metabolic heterogeneity of pancreatic cancer stem cells
Pancreatic cancer stem cells (CSCs) display a distinct metabolic phenotype based on their strong dependence on mitochondrial oxidative phosphorylation (OXPHOS) and limited metabolic plasticity. While suppression of MYC upstream of PGC-1α was the key determinant of this phenotype, we also identified...
में बचाया:
| में प्रकाशित: | Mol Cell Oncol |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Taylor & Francis
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905405/ https://ncbi.nlm.nih.gov/pubmed/27308630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1105353 |
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